The cast of The Simpsons transforms into Spider-Man villains!

Although the artist is unknown this photo of The Simpsons cast as Spider-Man villains (and Milhouse as a beat up Spider-Man) is truly fun. The character/villain match ups are great and in some cases eerily accurate. Which villain do you think is best represented here? Did your favorite Spider-Man villain make the piece?
*Click image to enlarge.

Source: Comic Book Movie